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Diabetic patients at Beijing's Aerospace Central Hospital have signed up for a new treatment which could mean an end to a life governed by daily insulin injections. º£ÀÌ¡ ¿ìÁÖÇ×°ø Áß¾Ó º´¿ø(Aerospace Cenral Hospital)ÀÇ ´ç´¢º´ ȯÀÚµéÀº »õ·Î¿î Ä¡·á¹ý¿¡ µ¿ÀÇÇß´Ù. ÀÌ·Î ÀÎÇØ ȯÀÚµéÀº ¸ÅÀÏ Àν¶¸° Áֻ縦 ¸Â¾Æ¾ß ÇÏ´Â »ýȰÀ» ³¡³¾ ¼öµµ ÀÖ´Ù.
Doctors at the hospital say the Hematopoietic Stem Cell Transplantation (HSCT) harnesses bone marrow stem cell to kick-start the insulin production process which a diabetic's body is unable to do on its own. Doctors have now treated 39 patients with both type 1 and 2 diabetes. ÀÌ º´¿ø ÀÇ»çµéÀº Á¶Ç÷¸ð¼¼Æ÷À̽Ä(HSCT) Ä¡·á¶õ Àν¶¸° »ý¼ºÀ» ½ÃÀÛÇϱâ À§ÇØ °ñ¼ö Áٱ⼼Æ÷¸¦ ÀÌ¿ëÇÏ´Â °ÍÀ̶ó°í ¼³¸íÇß´Ù. ´ç´¢º´ ȯÀÚÀÇ ¸öÀº ½º½º·Î Àν¶¸°À» ¸¸µéÁö ¸øÇÑ´Ù. ÀÇ»çµéÀº 1Çü, 2Çü ´ç´¢º´ ȯÀÚ 39¸íÀ» Ä¡·áÇß´Ù.
Patients who respond well to the operation can stop all medication or injections within 2 to 3 months, doctors say, although the timing of the result varies.Recovery from the operation takes several months. ¼ö¼ú °æ°ú°¡ ÁÁÀº ȯÀÚµéÀº µÎ¼¼ ´Þ ¾È¿¡ ¾à¹°Ä¡·á¸¦ ¸ØÃ߰ųª Àû¾îµµ Àν¶¸° ÁÖ»ç ÁÖÀÔÀ» Áß´ÜÇÒ ¼ö ÀÖ´Ù°í ÀÇ»çµéÀº ¸»ÇÑ´Ù. ¹°·Ð ±â°£Àº »ç¶÷¿¡ µû¶ó ´Þ¶óÁú ¼ö ÀÖ´Ù. ¼ö¼ú ÈÄ È¸º¹ÇÏ´Â µ¥ ¸î ´ÞÀÌ °É¸®´Â °æ¿ìµµ ÀÖ´Ù.
The hospital says 8 patients have healed altogether and are now entirely freed from their insulin injection routine.The rest are still in convalescence but doctors say they are also gradually reducing their reliance on their insulin injections. ÀÌ º´¿ø ÃøÀº ȯÀÚ 8¸íÀÌ ¿ÏÄ¡µÆÀ¸¸ç ½Ã°£¿¡ ¸ÂÃç Àν¶¸° Áֻ縦 ¸Â¾Æ¾ß ÇÏ´Â Àϻ󿡼 ¹þ¾î³µ´Ù°í ¸»Çß´Ù. ³ª¸ÓÁö ȯÀÚµéÀº ¿©ÀüÈ÷ ȸº¹ ÁßÀÌÁö¸¸ ¼¼È÷ Àν¶¸° ÁÖ»ç ÁÖÀÔÀ» ÁÙÀ̰í ÀÖ´Ù°í ¸»Çß´Ù.
While Wang Yizhong, chief physician of the hospital's Blood Endocrine Department, has seen no side effects to the treatment, he admits that it could be short-term and insulin deficiency may return after a few years. ÀÌ º´¿ø Ç÷¾× ³»ºÐºñ°ú ¼ö¼® ÀÇ»çÀÎ ¿ÕÀÌÁß ¾¾´Â ÀÌÁ¦±îÁö Ä¡·áÀÇ ºÎÀÛ¿ëÀº ³ªÅ¸³ªÁö ¾Ê¾Ò´Ù°í ¸»Çß´Ù. ±×´Â È¿°ú°¡ ´Ü±â°£¿¡ ±×Ä¥ ¼ö ÀÖÀ¸¸ç ¸î ³â µÚ Àν¶¸° ºÎÁ· Çö»óÀÌ Àç¹ßÇÒ ¼ö ÀÖ´Ù´Â »ç½ÇÀ» ÀÎÁ¤Çß´Ù.
However, Wang says this is not a problem as the procedure can be repeated."From one perspective, the operation is relatively cheap and it is not very painful to endure. If a patient can be medicine-free for 3 to 5 years it is already an accomplishment. If the symptoms come back after a couple of years we can always perform the operation again," he said. ÇÏÁö¸¸ ¿ÕÀÌÁß ¹Ú»ç´Â ±×·² °æ¿ì ´Ù½Ã ÀÌ½Ä ¼ö¼úÀ» ¹ÞÀ¸¸é µÇ±â ¶§¹®¿¡ Å« ¹®Á¦°¡ ¾È µÈ´Ù°í ¸»Çß´Ù. ¡°¶Ç ÇÑ °¡Áö Ãø¸éÀº ¼ö¼úÀÌ »ó´ëÀûÀ¸·Î ½Ñ µ¥´Ù °íÅëÀÌ ±×¸® ½ÉÇÏÁö ¾Ê´Ù´Â °ÍÀÌ´Ù. ¸¸¾à¿¡ ȯÀÚ°¡ ¾àÀ» ¸ÔÁö ¾Ê°í 3³â¿¡¼ 4³â±îÁö ¹öÆ¿ ¼ö ÀÖÀ¸¸é ±×°ÍÀ¸·Î Å« ¼º°øÀÌ´Ù. ¸î ³âÀÌ Áö³ µÚ Áõ»óÀÌ ´Ù½Ã ³ªÅ¸³ª¸é ´Ù½Ã ¼ö¼úÀ» ¹ÞÀ¸¸é µÈ´Ù.¡±
Zhang Xiaoyan is a type 2 diabetic patient who recently switched her diabetes medicine from pills to injections after her condition worsened.Zhang hates her two injections a day and is hoping to join the HSCT treatment waiting list.Along with the injections, Zhang is tired of watching what she eats, and says fighting cravings is the worst part of dealing with her illness."Food tastes so much better when you have diabetes, that's why we eat a lot. But when the doctor asks you to control how much you eat and what you eat, it is very tough," she said. ¾àÀ¸·Î Ä¡·áÇÏ´ø 2Çü ´ç´¢º´ ȯÀÚ Àå »þ¿À¿º ¾¾´Â ÃÖ±Ù »óŰ¡ ½É°¢ÇØÁ® Áֻ縦 ¸Â±â ½ÃÀÛÇß´Ù. Àå ¾¾´Â ¸ÅÀÏ ÇÏ·ç µÎ ¹ø¾¿ Àν¶¸° Áֻ縦 ¸Â´Â °Ô ½È´Ù¸ç HSCT Ä¡·á ´ë±âÀÚ ¸í´Ü¿¡ À̸§À» ¿Ã¸± ¼ö Àֱ⸦ Èñ¸ÁÇϰí ÀÖ´Ù. Àå ¾¾´Â ½Ä´ÜÀ» ½Å°æ¾²°í ¸Ô°í ½ÍÀº °ÍÀ» Âü¾Æ¾ß ÇÏ´Â °ÍÀÌ Åõº´ »ýȰÀÇ °¡Àå ¾î·Á¿î Á¡À̶ó°í ¸»Çß´Ù. ¡°´ç´¢º´¿¡ °É¸®¸é À½½Ä ¸ÀÀÌ ÈξÀ ÁÁ¾ÆÁø´Ù. ±×·¡¼ ¸¹ÀÌ ¸Ô°Ô µÈ´Ù. Àǻ簡 ½Ä´ÜÀ̳ª À½½Ä ¾çÀ» Á¤ÇØÁÖ¸é µû¸£±â°¡ Èûµé´Ù.¡±
However, doctors say HSCT treatment patients must still work on a restricted diet. During HSCT, drug injections stimulate the release of white blood cells from the patient's bone marrow. ÇÏÁö¸¸ ÀÇ»çµéÀº HSCT Ä¡·á¸¦ ¹Þ´Â ȯÀÚµéÀº ¾ö°ÝÇÏ°Ô ½Ä´ÜÀ» »ìÆì¾ß ÇÑ´Ù°í ¸»ÇÑ´Ù. HSCT Ä¡·á Áß¿¡ ¾à¹° Áֻ縦 ¸ÂÀ¸¸é °ñ¼ö¿¡¼ ¹éÇ÷±¸°¡ ¸¹ÀÌ ³ª¿Â´Ù.
The white blood cells that carry stem cells are collected through blood filtering and the harvested stem cells are then injected into the patient's pancreas to trigger insulin production. Ç÷¾× ¿©°ú¸¦ ÅëÇØ Áٱ⼼Æ÷°¡ Æ÷ÇÔµÈ ¹éÇ÷±¸¸¦ ¸ðÀº´Ù. ±×·± ´ÙÀ½ ȯÀÚÀÇ ÃéÀå¿¡ Áٱ⼼Æ÷¸¦ ÁÖÀÔÇϸé Àν¶¸°ÀÌ »ý¼ºµÈ´Ù.
The hospital performed its first HSCT treatment in January 2009 on a type 2 diabetes patient, and doctors say he is no longer reliant on his injections. ÀÌ º´¿øÀº 2009³â 1¿ù 2Çü ´ç´¢º´ ȯÀÚ¸¦ ´ë»óÀ¸·Î HSCT Ä¡·á¸¦ óÀ½À¸·Î ½Ç½ÃÇß´Ù. ÀÇ»çµéÀº ÀÌ Ã¹ ȯÀÚ°¡ ´õ ÀÌ»ó Àν¶¸° Áֻ縦 ¸ÂÁö ¾Ê´Â´Ù°í ¸»Çß´Ù.
According to some patients, HSCT not only regulates the blood sugar level, it can also take care of other diabetes symptoms, which insulin injections do not cure.Former patient Li Pingyuan was the ninth person to undergo HSCT treatment in China. ÀϺΠȯÀÚ´Â HSCT Ä¡·á°¡ Ç÷´ç ¼öÄ¡¸¦ Á¶ÀýÇØ ÁÙ »Ó¸¸ ¾Æ´Ï¶ó Àν¶¸° ÁÖ»ç·Î Ä¡·áÇÏÁö ¸øÇÏ´Â ´ç´¢º´À¸·Î ÀÎÇÑ ´Ù¸¥ Áõ»ó¿¡µµ È¿°ú°¡ ÀÖ´Ù°í ¸»Çß´Ù. Àü¿¡ ´ç´¢º´À» ¾Î¾Ò´ø ¸®ÇÎÀ§¾È ¾¾´Â Áß±¹¿¡¼ ¾ÆÈ©¹ø °·Î HSCT Ä¡·á¸¦ ¹ÞÀº »ç¶÷ÀÌ´Ù.
She says she is now completely insulin independent and that her eyesight has improved, but admits she had her doubts before submitting to the new treatment."I didn't understand the operation at first. I thought they would extract stem cells from my bone marrow to treat me, and it sounded so scary. I didn't have the right idea about stem cell transplants and I was very confused," she said. ¸®ÇÎÀ§¾È ¾¾´Â ÀÌÁ¦ Àν¶¸° Áֻ縦 ¿ÏÀüÈ÷ ²÷¾ú´Ù. ½Ã·Âµµ ÁÁ¾ÆÁö°í ÀÖ´Ù°í ÇÑ´Ù. ÇÏÁö¸¸ ±×³à´Â ÀÌ »õ Ä¡·á¹ý¿¡ µ¿ÀÇÇϱâ Àü¿¡ ÀǽÉÀÌ µé¾ú´Ù°í ¼ÖÁ÷È÷ ¸»Çß´Ù. ¡°³ª´Â óÀ½¿¡ À̽ļö¼úÀ» ÀÌÇØ ÇÏÁö ¸øÇß´Ù. ÀÇ·áÁøÀº ³» °ñ¼ö¿¡¼ Áٱ⠼¼Æ÷¸¦ ÃßÃâÇØ ³ª¸¦ Ä¡·áÇÒ °Å¶ó°í Çߴµ¥ ±×°Ô ³Ê¹« ¹«¼·°Ô µé·È´Ù. ³ª´Â Áٱ⠼¼Æ÷ À̽Ŀ¡ ´ëÇØ Àß ¾ËÁö ¸øÇ߱⠶§¹®¿¡ È¥¶õ½º·¯¿ü´Ù.¡±
The surgical procedure costs around 50,000 RMB (7,315 USD), it takes less than 2 hours and patients can leave the hospital within 2 weeks, doctors said. ÀÇ»çÀÇ ¼³¸í¿¡ µû¸£¸é ¼ö¼úÀ» ¹Þ´Âµ¥ µå´Â ºñ¿ëÀº 5¸¸ À§¾È(ÇÑÈ ¾à 940¸¸ ¿ø)ÀÌ´Ù. ¼ö¼ú ½Ã°£Àº 2½Ã°£µµ ä °É¸®Áö ¾ÊÀ¸¸ç ȯÀÚ´Â ¼ö¼ú ¹ÞÀº Áö 2ÁÖµµ ¾ÈµÅ Åð¿ø °¡´ÉÇÏ´Ù.
But beds are scarce. The hospital's schedule is fully booked for the next four months, in part thanks to a documentary on the treatment that aired on Chinese state television last month. ÇÏÁö¸¸ ÀÌ º´¿øÀº ȯÀÚ¸¦ ¼ö¿ëÇÒ °ø°£ÀÌ ºÎÁ·ÇÏ´Ù. 4°³¿ù °£ ¿¹¾àÀÌ ²Ë Â÷ ÀÖ´Ù. ÀÌ·¸°Ô ȯÀÚµéÀÇ ¹ÝÀÀÀÌ ¶ß°Å¿î °ÍÀº Áö³ ´Þ Áß±¹ °ü¿µ CCTV¿¡¼ ÀÌ Ä¡·á¿¡ ´ëÇÑ ´ÙÅ¥¸àÅ͸®¸¦ ¹æ¿µÇ߱⠶§¹®ÀÌ´Ù.
Beijing local Ju Jianhua had been battling type 2 diabetes for 15 years.Two weeks after his first HSCT treatment Ju was preparing to leave the hospital and said he already felt that the surgery had made a difference."For example, my legs used to hurt and they drove me crazy, but now, after the treatment, my legs feel a lot better and I can sleep soundly at night," he said. º£ÀÌ¡ ÁֹΠÁã ÄÈ ¾¾´Â 15³â °£ 2Çü ´ç´¢·Î °í»ýÇØ ¿Ô´Ù. ±×´Â HSCT Ä¡·á¸¦ óÀ½ ¹Þ°í 2ÁÖ°¡ °æ°úÇÑ ÈÄ Åð¿øÀ» ÁغñÇß´Ù. ±×´Â ¼ö¼ú ´öºÐ¿¡ ¹ú½á ¸öÀÌ ´Þ¶óÁ³À½À» ´À³¤´Ù°í ¸»Çß´Ù. "¿¹¸¦ µé¸é ³» ´Ù¸®´Â Ç×»ó ¾ÆÆÍ´Ù. ¾ÆÆÄ¼ ¹ÌÄ¥ °Í °°¾Ò´Ù. ÇÏÁö¸¸ ¼ö¼úÀ» ¹Þ°í ³ Áö±Ý ³» ´Ù¸® »óÅ´ ¸¹ÀÌ ³ª¾ÆÁ³´Ù. ¹ã¿¡µµ Æí¾ÈÇÏ°Ô ÀáÀ» Àß ¼ö ÀÖ´Ù"°í ±×°¡ ¸»Çß´Ù.
Beijing is currently the only place in the world to offer HSCT treatment to diabetes patients, according to Doctor Wang.According to state media there are close to 40 million diabetic patients in China and 246 million diabetic people around the world. ÇöÀç ´ç´¢º´ ȯÀÚ¿¡°Ô HSCT Ä¡·á¸¦ ÇÏ´Â °÷Àº ¼¼°è¿¡¼ º£ÀÌ¡ÀÌ À¯ÀÏÇÏ´Ù. °ü¿µ¾ð·Ð¿¡ µû¸£¸é Áß±¹ÀÇ ´ç´¢º´ ȯÀÚ´Â 4000¸¸ ¸í¿¡ ´ÞÇÏ°í ¼¼°èÀûÀ¸·Î´Â 2¾ï 4600¸¸ ¸íÀÌ ÀÖ´Ù.
Ten percent of adults in Beijing and Shanghai suffer from type 2 diabetes, according to the China Daily, while just 4 percent of adults living in rural areas are affected. Â÷À̳ª µ¥Àϸ®´Â º£ÀÌ¡°ú »óÇÏÀÌ¿¡ »ç´Â ¼ºÀÎ 10%°¡ 2Çü ´ç´¢·Î °í»ýÇϰí ÀÖ´Ù. ¹Ý¸é ³óÃÌ Áö¿ªÀº ¼ºÀÎ ³²¼º 4%°¡ ´ç´¢º´ ȯÀÚ¶ó°í º¸µµÇß´Ù.
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